Lixuan Mu is currently a researcher and doctoral supervisor at the Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences. She received her B. S. and M. S. degrees in chemistry from Shanxi University in 2001and 2004, respectively. In 2008, she received Ph.D. degree in condensed matter physics from Technical Institute of Physics andChemistry, Chinese Academy of Sciences. Her research focuses on the development and application of biosensors for single-cell analysis and early disease diagnosis.

1. Development of active single-cell detection technologies based on one‑dimensional nanostructures;
2. Controllable synthesis of noble metal nanoclusters and their applications in bioanalysis;
3. Construction of neuronal monitoring platforms and their application to studies of neurological disorders.

[1]. Lushan Huang, Liyi Ma, Qiaowen Zhao, Qichen Zhu, Guangwei She, Lixuan Mu,* and Wensheng Shi*，Simultaneous Imaging of pH and Peroxynitrite in the Endoplasmic Reticulum and Mitochondria: Revealing Organelle Interactions in Alzheimer’s Disease Pathogenesis, Analytial Chemistry, 2025, 97, 194.
[2]. Qiaowen Zhao, Liyi Ma, Siwei Chen , Lushan Huang , Guangwei She, Yongan Sun, Wensheng Shi*, Lixuan Mu *, Tracking mitochondrial Cu(I) fluctuations through a radiometric fluorescent probe in AD model cells: Towards understanding how AβOs induce mitochondrial Cu(I) dyshomeostasis, Talanta, 2024, 271, 125716.
[3]. Chenyuan Yan, Lixuan Mu,*  Mingliang Mei, Yuan Wang, Guangwei She, and Wensheng Shi*，Fluorescence Enhancement Method for Aptamer-Templated Silver Nanoclusters and Its Application in the Construction of a β-Amyloid Oligomer Sensor，Analytical Chemistry, 2023, 95, 6915−6922.
[4]. Yuan Wang, Qiaowen Zhao,  Sen Liang, Mingliang Mei, Guangwei She, Wensheng Shi* and Lixuan Mu*, Single nanowire-based fluorescence lifetime thermometer for simultaneous measurement of intra-and extra-cellular temperatures, Chemical Communications, 2023, 59, 4483.
[5]. Mingliang Mei, Lixuan Mu*, Yuan Wang, Sen Liang, Qiaowen Zhao, Lushan Huang, Guangwei She, Wensheng Shi*, Simultaneous Monitoring of the ATP levels in Cytoplasm and Nucleus of a Single Cell with Single Nanowire-Based Fluorescent Bio-sensor, Analytial Chemistry, 2022, 94, 11813-11820.
[6]. Yuan Wang, Sen Liang, Mingliang Mei, Qiaowen Zhao, Guangwei She, Wensheng Shi,* Lixuan Mu* , Sensitive and stable thermometer based on the long fluorescence lifetime of Au nanoclusters for mitochondria, Analytical Chemistry, 2021, 93, 15072.
[7].Mingliang Mei, Lixuan Mu,* Sen Liang, Yuan Wang, Guangwei She, Wensheng Shi, A general configurational strategy to quencher-free aptasensors, Biosensensors and Bioelectronics, 2021, 178, 113025.
[8]. Min Chen, Lixuan Mu*, Shuai Wang, Xingxing Cao, Sen Liang, Yuan Wang, Guangwei She, Jun Yang, Yongan Wang, and Wensheng Shi, A Single Silicon Nanowire-Based Ratiometric Biosensor for Ca2+ at Various Locations in a Neuron, ACS Chemical Neuroscience, 2020, 11, 1283-1290.
[9]. Congcong Bu, Lixuan Mu*, Xingxing Cao, Min Chen, Guangwei She, Wensheng Shi*. Silver nanowires-based fluorescence thermometer for single cell, ACS Applied Materials & Interfaces, 2018, 10, 33416.
[10]. Xingxing Cao, Lixuan Mu*, Min Chen, Congcong Bu, Sen Liang, Guangwei She, Wensheng Shi* Single silicon nanowire-based fluorescent sensor for endogenous hypochlorite in an individual cell, Advanced Biosystems, 2018, 1800213.