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| Project of "Advanced Technology on Production of Vitamin D3" won the National Scientific and Technological Advancement Award (Grade II) for 2007 |
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China granted its National Science and Technology Awards for 2007 at the Great Hall of the People, Beijing, on Jan. 8, 2008. Chinese President Hu Jintao, presented the State Scientific and Technological Award to the petrochemical scientist Min Enze and the botanist Wu Zhengyi for their outstanding achievements. Premier Wen Jiabao and other Party and government leaders, Li Changchun, Xi Jinping and Li Keqiang, also attended the event and presented awards to other scientists and enterprises for their significant scientific contributions. Technical Institute of Physics and Chemistry, CAS, honorably became one of the winners for the Scientific and Technological Advancement Award (Grade II) by virtue of the project of "Advanced Technology on Production of Vitamin D3".
The technique of vitamin D3 (VD3) production was monopolized by several foreign companies for several decades and the need of VD3 in our country had to depend totally on the importation. The research group led by Prof. Yi Cao and Prof. Baowen Zhang successfully applied novel strategies and techniques to prepare VD3 in the scale of pilot plant and more importantly in the overall yield of 44%, higher than that of the traditional technique by 10%. The main technical inventions include (1) synthesis of 7-dehydrocholesterol by a bromine-free procedure; (2) photoreaction in a medium of mixed solvents; (3) application of new type of photoreactor; and (4) real-time monitoring methods of the photoreaction.
This innovative technology was transferred to HuaYuan company, a private enterprice located in ZheJiang Province, in 2000. Up to the end of 2006, the total sales of VD3-related products of HuaYuan company has mounted over 1.7 billion Yuan (RMB).
Lu yongxiang, the present of CAS, sent a congratulation letter on behalf of the party committee of CAS to Technical Institute of Physics and Chemistry and the all project participants of "Advanced Technology on Production of Vitamin D3".
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