[Ru(bpy)2(py-SO3)]+ (bpy = 2,2′-bipyridine and py-SO3 = pyridine-2-sulfonate) was found to undergo py-SO3 dissociation upon visible light irradiation (≥470 nm) via Ru–O homolysis, producing reactive free radical species, and is thus able to not only photobind but also photocleave DNA in hypoxic conditions. Chem. Commun., 2015 EPR signals obtained after laser irradiation (355 nm) of an Ar-saturated CH3CN solution of [Ru(bpy)2(py-SO3)]+ (1 mM) and DMPO (50 mM). A possible mechanism for DMPOX formation in the case of [Ru(bpy)2(py-SO3)]+. |
